Quantitative study of BSA coating silica nanoparticle
© 2014, Springer International Publishing Switzerland. The loading of biomolecules on nanoparticles might be thought of as a first step to design a cargo in drug delivery system. Here, we study a quantity of bovine serum albumin (BSA) surrounding the silica nanoparticle. The silica nanoparticle is m...
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th-mahidol.336482018-11-09T09:30:56Z Quantitative study of BSA coating silica nanoparticle Duangkamon Baowan Volkhard Helms Mahidol University Universitat des Saarlandes Chemistry Mathematics © 2014, Springer International Publishing Switzerland. The loading of biomolecules on nanoparticles might be thought of as a first step to design a cargo in drug delivery system. Here, we study a quantity of bovine serum albumin (BSA) surrounding the silica nanoparticle. The silica nanoparticle is modeled as a perfect sphere whereas the BSA is represented by an ellipsoid. On utilizing a continuous approximation, the electrostatic and van der Waals interactions can be analytically expressed. Further, a number of BSA molecules coating on the nanoparticles of various sizes can be simply determined as a function of the protein ring radius. Our finding is in a good agreement found in experiment and this can be a guide to evaluate the number of protein on other type of spherical nanoparticles. 2018-11-09T02:07:21Z 2018-11-09T02:07:21Z 2014-01-01 Article Journal of Mathematical Chemistry. Vol.53, No.1 (2014), 29-40 10.1007/s10910-014-0408-z 02599791 2-s2.0-84921936489 https://repository.li.mahidol.ac.th/handle/123456789/33648 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84921936489&origin=inward |
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© 2014, Springer International Publishing Switzerland. The loading of biomolecules on nanoparticles might be thought of as a first step to design a cargo in drug delivery system. Here, we study a quantity of bovine serum albumin (BSA) surrounding the silica nanoparticle. The silica nanoparticle is modeled as a perfect sphere whereas the BSA is represented by an ellipsoid. On utilizing a continuous approximation, the electrostatic and van der Waals interactions can be analytically expressed. Further, a number of BSA molecules coating on the nanoparticles of various sizes can be simply determined as a function of the protein ring radius. Our finding is in a good agreement found in experiment and this can be a guide to evaluate the number of protein on other type of spherical nanoparticles. |
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Mahidol University Duangkamon Baowan Volkhard Helms |
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Duangkamon Baowan Volkhard Helms |
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Quantitative study of BSA coating silica nanoparticle |
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Quantitative study of BSA coating silica nanoparticle |
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Quantitative study of BSA coating silica nanoparticle |
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Quantitative study of BSA coating silica nanoparticle |
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Quantitative study of BSA coating silica nanoparticle |
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quantitative study of bsa coating silica nanoparticle |
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2018 |
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