Transient increase of interferon-stimulated genes and no clinical benefit by chloroquine treatment during acute simian immunodeficiency virus infection of macaques

Transient increase of interferon-stimulated genes and no clinical benefit by chloroquine treatment during acute simian immunodeficiency virus infection of macaques

Simian immunodeficiency virus (SIV) infection leads to AIDS in experimentally infected Rhesus macaques similarly to HIV-infected humans. In contrast, SIV infection of natural hosts is characterized by a down-regulation of innate acute responses to the virus within a few weeks of infection and result...

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Bibliographic Details
Main Authors: Monica Vaccari, Claudio Fenizia, Zhong Min Ma, Anna Hryniewicz, Adriano Boasso, Melvin N. Doster, Christopher J. Miller, Niklas Lindegardh, Joel Tarning, Alan L. Landay, Gene M. Shearer, Genoveffa Franchini
Other Authors: National Cancer Institute
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/33978
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/33978

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