Screening for lead compounds and herbal extracts with potential anti-influenza viral activity

Nonstructural protein 1 (NS1) of the highly pathogenic avian influenza virus (H5N1) contains a conserved RNA binding domain (RBD) that inhibits antiviral functions of host-innate immune response. Dimerization of NS1 forms a central groove and binds to double stranded (ds) RNA. This region might serv...

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Bibliographic Details
Main Authors: Konrapob Klaywong, Gachagorn Khutrakul, Kiattawee Choowongkomon, Chalermpol Lekcharoensuk, Nantawan Petcharat, Porntippa Leckcharoensuk, Pongrama Ramasoota
Other Authors: Kasetsart University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/34444
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Institution: Mahidol University