Deleterious effect of oltipraz on extrahepatic cholestasis in bile duct-ligated mice

Background & Aims Oltipraz (4-methyl-5(pyrazinyl-2)-1-2-dithiole-3- thione), a promising cancer preventive agent, has an antioxidative activity and ability to enhance glutathione biosynthesis, phase II detoxification enzymes and multidrug resistance-associated protein-mediated efflux transporter...

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Bibliographic Details
Main Authors: Jittima Weerachayaphorn, Yuhuan Luo, Albert Mennone, Carol J. Soroka, Kathy Harry, James L. Boyer
Other Authors: Yale University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/34479
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Institution: Mahidol University