Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation

Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation

Caspase-3-mediated spontaneous death in neutrophils is a prototype of programmed cell death and is critical for modulating physiopathological inflammatory responses; however, the underlying regulatory pathways remain ill defined. Here we determined that in aging neutrophils, the cleavage and activat...

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Bibliographic Details
Main Authors: Fabien Loison, Haiyan Zhu, Kutay Karatepe, Anongnard Kasorn, Peng Liu, Keqiang Ye, Jiaxi Zhou, Shannan Cao, Haiyan Gong, Dieter E. Jenne, Eileen Remold-O'Donnell, Yuanfu Xu, Hongbo R. Luo
Other Authors: Children's Hospital Boston
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/34813
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/34813

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