Antimicrobial host defence peptide, LL-37, as a potential vaginal contraceptive

STUDY QUESTIONDoes antimicrobial peptide, LL-37, inhibit sperm fertilizing ability?SUMMARY ANSWEROur results indicate that LL-37 inhibits mouse and human sperm fertilizing ability.WHAT IS KNOWN ALREADYLL-37, a cationic antimicrobial peptide, exerts its microbicidal effects through the disruption of...

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Main Authors: Nopparat Srakaew, Charlene D. Young, Arpornrad Sae-Wu, Hongbin Xu, Krista L. Quesnel, Riccardo Di Brisco, Kessiri Kongmanas, Duriya Fongmoon, Greanggrai Hommalai, Wattana Weerachatyanukul, Susan H. Hall, Yong Lian Zhang, Luigi Panza, Laura Franchini, Federica Compostella, Terry W. Pearson, Robert E. Hancock, Richard J. Oko, Louis S. Hermo, Nongnuj Tanphaichitr
Other Authors: Ottawa Hospital Research Institute
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/34853
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Institution: Mahidol University