A genetically immortalized human stem cell line: A promising new tool for Alzheimer’s disease therapy

• Main Authors: Nicha Puangmalai, Alyma Somani, Wipawan Thangnipon, Clive Ballard, Martin Broadstock
• Other Authors: King's College London
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/35085
• Institution: Mahidol University

© 2015, Leibniz Research Centre for Working Environment and Human Factors. All rights reserved. Amyloid-β peptides and hyper-phosphorylated tau are the main pathological hallmarks of Alzheimer’s disease (AD). Given the recent failure of several large-scale clinical trials and the lack of disease-mod...