Classification of p-glycoprotein-interacting compounds using machine learning methods

• Main Authors: Veda Prachayasittikul, Apilak Worachartcheewan, Watshara Shoombuatong, Virapong Prachayasittikul, Chanin Nantasenamat
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/35114

© 2015 Leibniz Research Centre for Working Environment and Human Factors. All rights reserved. P-glycoprotein (Pgp) is a drug transporter that plays important roles in multidrug resistance and drug pharmacokinetics. The inhibition of Pgp has become a notable strategy for combating multidrug-resistan...