Antitumor efficacy and intratumoral distribution of SN-38 from polymeric depots in brain tumor model

• Main Authors: Ketpat Vejjasilpa, Norased Nasongkla, Chawan Manaspon, Noppadol Larbcharoensub, Atthaporn Boongird, Suradej Hongeng, Nipan Israsena
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/35339

© 2015, © 2015 by the Society for Experimental Biology and Medicine. We investigate antitumor efficacy and 2D and 3D intratumoral distribution of 7-ethyl-10-hydroxycamptothecin (SN-38) from polymeric depots inside U-87MG xenograft tumor model in nude mice. Results showed that polymeric depots could...