Actinoallolides A-E, new anti-trypanosomal macrolides, produced by an endophytic actinomycete, actinoallomurus fulvus MK10-036

• Main Authors: Yuki Inahashi, Masato Iwatsuki, Aki Ishiyama, Atsuko Matsumoto, Tomoyasu Hirose, Jun Oshita, Toshiaki Sunazuka, Watanalai Panbangred, Yoko Takahashi, Marcel Kaiser, Kazuhiko Otoguro, Satoshi O'mura
• Other Authors: Kitasato University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/35498
• Institution: Mahidol University

© 2015 American Chemical Society. Five new anti-trypanosomal macrolides, actinoallolides A-E (1-5), were discovered from the cultured broth of Actinoallomurus fulvus MK10-036. The structures of the actinoallolides, including absolute stereochemistry, were elucidated by a combination of spectroscopic...