New mutations of the ID1 gene in acute myeloid leukemia patients

• Main Authors: Chintana Tochareontanaphol, Thivaratana Sinthuwiwat, Borisuit Buathong, Thunyatip Thita, Somying Promso, Saowakon Paca-Uccaralertkun
• Other Authors: Chulabhorn Hospital
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/35606
• Institution: Mahidol University

© 2015 S. Karger AG, Basel. Objectives: Overexpression of the inhibitor of DNA binding 1 (ID1) protein is found in many types of cancer. In acute myeloid leukemia (AML), the expression of ID1 is induced by abnormal tyrosine kinases, such as FLT3 and BCR-ABL. High level expression of ID1 is associate...