Iodine-catalyzed oxidative cross-coupling of indoles and azoles: Regioselective synthesis of N -linked 2-(Azol-1-yl)indole derivatives

© 2015 American Chemical Society. A highly efficient iodine-catalyzed regioselective oxidative cross-coupling of an indole C-H bond and azole N-H bond is described. This metal-free reaction can be easily carried out at room temperature under mild and environmentally friendly conditions and provides...

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Bibliographic Details
Main Authors: Danupat Beukeaw, Kwanchanok Udomsasporn, Sirilata Yotphan
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/35753
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Institution: Mahidol University
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Summary:© 2015 American Chemical Society. A highly efficient iodine-catalyzed regioselective oxidative cross-coupling of an indole C-H bond and azole N-H bond is described. This metal-free reaction can be easily carried out at room temperature under mild and environmentally friendly conditions and provides a series of N-linked 2-(azol-1-yl)indole derivatives in moderate to excellence yields.