Integrated microfluidic card with taqman probes and high- resolution melt analysis to detect tuberculosis drug resistance mutations across 10 genes

• Main Authors: Suporn Pholwat, Jie Liu, Suzanne Stroup, Jean Gratz, Sayera Banu, S. M. Mazidur Rahman, Sara Sabrina Ferdous, Suporn Foongladda, Duangjai Boonlert, Oleg Ogarkov, Svetlana Zhdanova, Gibson Kibiki, Scott Heysell, Eric Houpt
• Other Authors: University of Virginia
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/36123
• Institution: Mahidol University

© 2015 Pholwat et al. Genotypic methods for drug susceptibility testing of Mycobacterium tuberculosis are desirable to speed the diagnosis and proper therapy of tuberculosis (TB). However, the numbers of genes and polymorphisms implicated in resistance have proliferated, challenging diagnostic desig...