Adenovirus-based HIV-1 vaccine candidates tested in efficacy trials elicit CD8 + T cells with limited breadth of HIV-1 inhibition

Adenovirus-based HIV-1 vaccine candidates tested in efficacy trials elicit CD8 + T cells with limited breadth of HIV-1 inhibition

Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. Objectives: The ability of HIV-1 vaccine candidates MRKAd5, VRC DNA/Ad5 and ALVAC/AIDSVAX to elicit CD8 + T cells with direct antiviral function was assessed and compared with HIV-1-infected volunteers. Design: Adenovirus serotype 5 (...

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Main Authors: Peter J. Hayes, Josephine H. Cox, Adam R. Coleman, Natalia Fernandez, Philip J. Bergin, Jakub T. Kopycinski, Sorachai Nitayaphan, Punnee Pitisuttihum, Mark De Souza, Ann Duerr, Cecilia Morgan, Jill W. Gilmour
Other Authors: Chelsea and Westminster Hospital
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/40775
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/40775

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