Optimal design strategies for relative potency using the two-parameter log-logistic model
© 2016 - IOS Press and the authors. All rights reserved. In this paper, we focus on the D- and Ds-optimal designs for two-parameter log-logistic (LL2) relative potency model where the response variables are normal and binomial distributions. The D- and Ds-optimal designs are obtained by using D-opti...
Saved in:
| Main Authors: | , , |
|---|---|
| 其他作者: | |
| 格式: | Article |
| 出版: |
2018
|
| 主題: | |
| 在線閱讀: | https://repository.li.mahidol.ac.th/handle/123456789/40935 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|
| 機構: | Mahidol University |
| 總結: | © 2016 - IOS Press and the authors. All rights reserved. In this paper, we focus on the D- and Ds-optimal designs for two-parameter log-logistic (LL2) relative potency model where the response variables are normal and binomial distributions. The D- and Ds-optimal designs are obtained by using D-optimal design and nesting strategy criterions, respectively. Furthermore, the general equivalence theorems is used to guarantee the D- and Ds-optimal designs. The results show that we obtain four support points for D-optimal designs and two support points for Ds-optimal designs. |
|---|