A key enzyme of the NAD⁺salvage pathway in Thermus thermophilus: Characterization of nicotinamidase and the impact of its gene deletion at high temperatures

• Main Authors: Hironori Taniguchi, Sathidaphorn Sungwallek, Phatcharin Chotchuang, Kenji Okano, Kohsuke Honda
• Other Authors: Osaka University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/41740
• Institution: Mahidol University

© 2017 American Society for Microbiology. All Rights Reserved. NAD (NAD+) is a cofactor related to many cellular processes. This cofactor is known to be unstable, especially at high temperatures, where it chemically decomposes to nicotinamide and ADP-ribose. Bacteria, yeast, and higher organisms pos...