Error-Prone Splicing Controlled by the Ubiquitin Relative Hub1

© 2017 Elsevier Inc. Accurate pre-mRNA splicing is needed for correct gene expression and relies on faithful splice site recognition. Here, we show that the ubiquitin-like protein Hub1 binds to the DEAD-box helicase Prp5, a key regulator of early spliceosome assembly, and stimulates its ATPase activ...

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Bibliographic Details
Main Authors: Ramazan Karaduman, Sittinan Chanarat, Boris Pfander, Stefan Jentsch
Other Authors: Max Planck Institute of Biochemistry
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/41807
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Institution: Mahidol University