Genome-wide identification of lineage and locus specific variation associated with pneumococcal carriage duration

• Main Authors: John A. Lees, Nicholas J. Croucher, David Goldblatt, François Nosten, Julian Parkhill, Claudia Turner, Paul Turner, Stephen D. Bentley
• Other Authors: Wellcome Trust Sanger Institute
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/41834
• Institution: Mahidol University

© Lees et al. Streptococcus pneumoniae is a leading cause of invasive disease in infants, especially in low-income settings. Asymptomatic carriage in the nasopharynx is a prerequisite for disease, but variability in its duration is currently only understood at the serotype level. Here we developed a...