Towards predicting the cytochrome P450 modulation: From QSAR to proteochemometric modeling

• Main Authors: Watshara Shoombuatong, Philip Prathipati, Veda Prachayasittikul, Nalini Schaduangrat, Aijaz Ahmad Malik, Reny Pratiwi, Sompon Wanwimolruk, Jarl E.S. Wikberg, Matthew Paul Gleeson, Ola Spjuth, Chanin Nantasenamat
• Other Authors: Mahidol University
• Format: Review
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/41880

©2017 Bentham Science Publishers. Drug metabolism determines the fate of a drug when it enters the human body and is a critical factor in defining their absorption, distribution, metabolism, excretion and toxicity (ADMET) characteristics. Among the various drug metabolizing enzymes, cytochrome P450s...