Functional analysis of the mammalian RNA ligase for IRE1 in the unfolded protein response

© 2017 The Author(s). The unfolded protein response (UPR) is a conserved signalling pathway activated on the accumulation of unfolded proteins within the endoplasmic reticulum (ER), termed ER stress. Upon ER stress, HAC1/XBP1 undergoes exon/intron-specific excision by inositol requiring enzyme 1 (IR...

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Bibliographic Details
Main Authors: Juthakorn Poothong, Witoon Tirasophon, Randal J. Kaufman
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/41919
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Institution: Mahidol University