Fibroblast growth factor-21 restores insulin sensitivity but induces aberrant bone microstructure in obese insulin-resistant rats

• Main Authors: Narattaphol Charoenphandhu, Panan Suntornsaratoon, Nateetip Krishnamra, Piangkwan Sa-nguanmoo, Pongpun Tanajak, Xiaojie Wang, Guang Liang, Xiaokun Li, Chao Jiang, Nipon Chattipakorn, Siriporn Chattipakorn
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/41966

© 2016, The Japanese Society for Bone and Mineral Research and Springer Japan. Fibroblast growth factor (FGF)-21 is a potent endocrine factor that improves insulin resistance and obesity-associated metabolic disorders. However, concomitant activation of peroxisome proliferator-activated receptor-γ b...