Design and construction of a synthetic E. coli protease inhibitor detecting biomachine

• Main Authors: P. Boonyalekha, A. Meechai, C. Tayapiwatana, K. Kitidee, D. Waraho-Zhmayev
• Other Authors: King Mongkut s University of Technology Thonburi
• Format: Conference or Workshop Item
• Published: 2018
• Subjects: Computer Science; Engineering
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/42328
• Institution: Mahidol University

© 2017 IEEE. Protease inhibitors (PIs) have been used to treat various types of symptoms or diseases. However, current PIs block the protease activity by targeting the protease active site which has been shown to be sensitive to the off-target effect due to crossreactivity with protease homologues....