Preformation Versus Epigenesis in Early Mammalian Development
© 2016 Elsevier Inc. Whether or not early mammalian development results from preformation or epigenesis remains an unresolved issue. Evidence for or against either is weak, inconclusive, and often misinterpreted. Yet, one can parsimoniously conceptualize formation of the mouse blastocyst as a series...
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th-mahidol.426922019-03-14T15:03:43Z Preformation Versus Epigenesis in Early Mammalian Development Davor Solter Mahidol University Max Planck Institute of Immunobiology and Epigenetics Biochemistry, Genetics and Molecular Biology © 2016 Elsevier Inc. Whether or not early mammalian development results from preformation or epigenesis remains an unresolved issue. Evidence for or against either is weak, inconclusive, and often misinterpreted. Yet, one can parsimoniously conceptualize formation of the mouse blastocyst as a series of random, stochastic events stemming from initial and sequential small asymmetries in egg, zygote, and cleavage stages. Differential compartmentalized gene expression does not lead but follows the morphogenesis and cell fate allocation in the mammalian blastocyst. 2018-12-11T02:05:50Z 2019-03-14T08:03:43Z 2018-12-11T02:05:50Z 2019-03-14T08:03:43Z 2016-12-01 Chapter Current Topics in Developmental Biology. Vol.117, (2016), 377-391 10.1016/bs.ctdb.2015.11.006 00702153 2-s2.0-84955574680 https://repository.li.mahidol.ac.th/handle/123456789/42692 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84955574680&origin=inward |
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Biochemistry, Genetics and Molecular Biology Davor Solter Preformation Versus Epigenesis in Early Mammalian Development |
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© 2016 Elsevier Inc. Whether or not early mammalian development results from preformation or epigenesis remains an unresolved issue. Evidence for or against either is weak, inconclusive, and often misinterpreted. Yet, one can parsimoniously conceptualize formation of the mouse blastocyst as a series of random, stochastic events stemming from initial and sequential small asymmetries in egg, zygote, and cleavage stages. Differential compartmentalized gene expression does not lead but follows the morphogenesis and cell fate allocation in the mammalian blastocyst. |
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Mahidol University Davor Solter |
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Chapter |
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Davor Solter |
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Davor Solter |
| title |
Preformation Versus Epigenesis in Early Mammalian Development |
| title_short |
Preformation Versus Epigenesis in Early Mammalian Development |
| title_full |
Preformation Versus Epigenesis in Early Mammalian Development |
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Preformation Versus Epigenesis in Early Mammalian Development |
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Preformation Versus Epigenesis in Early Mammalian Development |
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preformation versus epigenesis in early mammalian development |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/42692 |
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