Sensitive luminescent reporter viruses reveal appreciable release of hepatitis C virus NS5A protein into the extracellular environment

Sensitive luminescent reporter viruses reveal appreciable release of hepatitis C virus NS5A protein into the extracellular environment

© 2017 Elsevier Inc. The HCV NS5A protein is essential for viral RNA replication and virus particle assembly. To study the viral replication cycle and NS5A biology we generated an infectious HCV construct with a NanoLuciferase (NLuc) insertion within NS5A. Surprisingly, beyond its utility as a sensi...

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Bibliographic Details
Main Authors: Nicholas S. Eyre, Amanda L. Aloia, Michael A. Joyce, Monrat Chulanetra, D. Lorne Tyrrell, Michael R. Beard
Other Authors: The University of Adelaide
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/42789
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/42789

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