Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

• Main Authors: Chiea Chuen Khor, Tan Do, Hongyan Jia, Masakazu Nakano, Ronnie George, Khaled Abu-Amero, Roopam Duvesh, Li Jia Chen, Zheng Li, Monisha E. Nongpiur, Shamira A. Perera, Chunyan Qiao, Hon Tym Wong, Hiroshi Sakai, Mônica Barbosa De Melo, Mei Chin Lee, Anita SChan, Yaakub Azhany, Thi Lam Huong Dao, Yoko Ikeda, Rodolfo A. Perez-Grossmann, Tomasz Zarnowski, Alexander C. Day, Jost B. Jonas, Pancy O.S. Tam, Tuan Anh Tran, Humaira Ayub, Farah Akhtar, Shazia Micheal, Paul T.K. Chew, Leyla A. Aljasim, Tanuj Dada, Tam Thi Luu, Mona S. Awadalla, Naris Kitnarong, Boonsong Wanichwecharungruang, Yee Yee Aung, Jelinar Mohamed-Noor, Saravanan Vijayan, Sripriya Sarangapani, Rahat Husain, Aliza Jap, Mani Baskaran, David Goh, Daniel H. Su, Huaizhou Wang, Vernon K. Yong, Leonard W. Yip, Tuyet Bach Trinh, Manchima Makornwattana, Thanh Thu Nguyen, Edgar U. Leuenberger, Ki Ho Park, Widya Artini Wiyogo, Rajesh SKumar, Celso Tello, Yasuo Kurimoto, Suman S. Thapa, Kessara Pathanapitoon, John F. Salmon, Yong Ho Sohn, Antonio Fea, Mineo Ozaki, Jimmy S.M. Lai, Visanee Tantisevi, Chaw Chaw Khaing, Takanori Mizoguchi, Satoko Nakano, Chan Yun Kim, Guangxian Tang, Sujie Fan, Renyi Wu, Hailin Meng, Thi Thuy Giang Nguyen, Tien Dat Tran, Morio Ueno, Jose Maria Martinez, Norlina Ramli, Yin Mon Aung, Rigo Daniel Reyes, Stephen A. Vernon, Seng Kheong Fang, Zhicheng Xie, Xiao Yin Chen, Jia Nee Foo
• Other Authors: A-Star, Genome Institute of Singapore
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/43017
• Institution: Mahidol University

© 2016 Nature America, Inc. Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We conducted a genome-wide association study (GWAS) followed by replication in a combined total of 10,503 PACG cases and 29,567 controls drawn from 24 countries across Asia, Australia, Europe,...