Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida

Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida

© 2016 The Royal Society of Chemistry. A library of 33 compounds was screened for potentiation of the antibiotic FR 900098 against the Francisella tularensis surrogate Francisella novicida. From the screen a highly potent 2-oxazoline adjuvant was discovered capable of potentiating FR 900098 with a 1...

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Main Authors: Matthew D. Stephens, Nisakorn Yodsanit, Christian Melander
Other Authors: North Carolina State University
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/43169
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spelling th-mahidol.431692019-03-14T15:04:15Z Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida Matthew D. Stephens Nisakorn Yodsanit Christian Melander North Carolina State University Mahidol University Biochemistry, Genetics and Molecular Biology © 2016 The Royal Society of Chemistry. A library of 33 compounds was screened for potentiation of the antibiotic FR 900098 against the Francisella tularensis surrogate Francisella novicida. From the screen a highly potent 2-oxazoline adjuvant was discovered capable of potentiating FR 900098 with a 1000-fold reduction in MIC against the Francisella sub-species F. novicida and F. philomiragia. 2018-12-11T02:23:03Z 2019-03-14T08:04:15Z 2018-12-11T02:23:03Z 2019-03-14T08:04:15Z 2016-01-01 Article MedChemComm. Vol.7, No.10 (2016), 1952-1956 10.1039/c6md00365f 20402511 20402503 2-s2.0-84991404778 https://repository.li.mahidol.ac.th/handle/123456789/43169 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84991404778&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Biochemistry, Genetics and Molecular Biology
spellingShingle Biochemistry, Genetics and Molecular Biology
Matthew D. Stephens
Nisakorn Yodsanit
Christian Melander
Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida
description © 2016 The Royal Society of Chemistry. A library of 33 compounds was screened for potentiation of the antibiotic FR 900098 against the Francisella tularensis surrogate Francisella novicida. From the screen a highly potent 2-oxazoline adjuvant was discovered capable of potentiating FR 900098 with a 1000-fold reduction in MIC against the Francisella sub-species F. novicida and F. philomiragia.
author2 North Carolina State University
author_facet North Carolina State University
Matthew D. Stephens
Nisakorn Yodsanit
Christian Melander
format Article
author Matthew D. Stephens
Nisakorn Yodsanit
Christian Melander
author_sort Matthew D. Stephens
title Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida
title_short Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida
title_full Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida
title_fullStr Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida
title_full_unstemmed Potentiation of the fosmidomycin analogue FR 900098 with substituted 2-oxazolines against Francisella novicida
title_sort potentiation of the fosmidomycin analogue fr 900098 with substituted 2-oxazolines against francisella novicida
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/43169
_version_ 1763497957997412352

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