F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system

© The Royal Society of Chemistry. F-THENA is designed as an alternative fluorine-containing chiral derivatizing agent (CDA). The fluorine atom functions exclusively as a reporter which can directly sense an anisotropic effect from an aromatic substituent of a chiral alcohol. In combination with chem...

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Main Authors: Kulvadee Dolsophon, Jakapun Soponpong, Jittra Kornsakulkarn, Chawanee Thongpanchang, Samran Prabpai, Palangpon Kongsaeree, Tienthong Thongpanchang
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/43220
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spelling th-mahidol.432202019-03-14T15:04:18Z F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system Kulvadee Dolsophon Jakapun Soponpong Jittra Kornsakulkarn Chawanee Thongpanchang Samran Prabpai Palangpon Kongsaeree Tienthong Thongpanchang Mahidol University Thailand National Center for Genetic Engineering and Biotechnology Biochemistry, Genetics and Molecular Biology Chemistry © The Royal Society of Chemistry. F-THENA is designed as an alternative fluorine-containing chiral derivatizing agent (CDA). The fluorine atom functions exclusively as a reporter which can directly sense an anisotropic effect from an aromatic substituent of a chiral alcohol. In combination with chemical shift differences from both19F NMR and1H NMR, the F-THENA method can successfully be used for determining the absolute configuration of chiral secondary aromatic alcohols with a self-validating system. 2018-12-11T02:25:02Z 2019-03-14T08:04:18Z 2018-12-11T02:25:02Z 2019-03-14T08:04:18Z 2016-01-01 Article Organic and Biomolecular Chemistry. Vol.14, No.46 (2016), 11002-11012 10.1039/C6OB02255C 14770520 2-s2.0-84998704813 https://repository.li.mahidol.ac.th/handle/123456789/43220 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84998704813&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Biochemistry, Genetics and Molecular Biology
Chemistry
spellingShingle Biochemistry, Genetics and Molecular Biology
Chemistry
Kulvadee Dolsophon
Jakapun Soponpong
Jittra Kornsakulkarn
Chawanee Thongpanchang
Samran Prabpai
Palangpon Kongsaeree
Tienthong Thongpanchang
F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system
description © The Royal Society of Chemistry. F-THENA is designed as an alternative fluorine-containing chiral derivatizing agent (CDA). The fluorine atom functions exclusively as a reporter which can directly sense an anisotropic effect from an aromatic substituent of a chiral alcohol. In combination with chemical shift differences from both19F NMR and1H NMR, the F-THENA method can successfully be used for determining the absolute configuration of chiral secondary aromatic alcohols with a self-validating system.
author2 Mahidol University
author_facet Mahidol University
Kulvadee Dolsophon
Jakapun Soponpong
Jittra Kornsakulkarn
Chawanee Thongpanchang
Samran Prabpai
Palangpon Kongsaeree
Tienthong Thongpanchang
format Article
author Kulvadee Dolsophon
Jakapun Soponpong
Jittra Kornsakulkarn
Chawanee Thongpanchang
Samran Prabpai
Palangpon Kongsaeree
Tienthong Thongpanchang
author_sort Kulvadee Dolsophon
title F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system
title_short F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system
title_full F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system
title_fullStr F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system
title_full_unstemmed F-THENA: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system
title_sort f-thena: a chiral derivatizing agent for the determination of the absolute configuration of secondary aromatic alcohols with a self-validating system
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/43220
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