Associations between HLA class i and cytochrome P450 2C9 genetic polymorphisms and phenytoin-related severe cutaneous adverse reactions in a Thai population

• Main Authors: Wichittra Tassaneeyakul, Napat Prabmeechai, Chonlaphat Sukasem, Thachanan Kongpan, Parinya Konyoung, Pansu Chumworathayi, Somsak Tiamkao, Usanee Khunarkornsiri, Kongkiat Kulkantrakorn, Niwat Saksit, Nontaya Nakkam, Patompong Satapornpong, Suda Vannaprasaht, Alisara Sangviroon, Surakameth Mahasirimongkol, Nuanjun Wichukchinda, Ticha Rerkpattanapipat, Wongwiwat Tassaneeyakul
• Other Authors: Khon Kaen University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/43229
• Institution: Mahidol University

© 2016 Wolters Kluwer Health, Inc. All rights reserved. Background Phenytoin is one of the most common causative drugs of several types of severe cutaneous adverse reactions (SCAR) such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reactions with eosinophilia and syst...