Thienopyrimidine sulphonamide hybrids: Design, synthesis, antiprotozoal activity and molecular docking studies

Thienopyrimidine sulphonamide hybrids: Design, synthesis, antiprotozoal activity and molecular docking studies

© 2016 The Royal Society of Chemistry. A series of hybrid compounds containing the thienopyrimidine scaffold as a DHFR inhibitor fused with a bioactive sulphonamide piperazine skeleton were synthesized and evaluated against the chloroquine and pyrimethamine resistant K1 strain of Plasmodium falcipar...

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Bibliographic Details
Main Authors: Saadia Leeza Zaidi, Subhash M. Agarwal, Porntip Chavalitshewinkoon-Petmitr, Thidarat Suksangpleng, Kamal Ahmad, Fernando Avecilla, Amir Azam
Other Authors: Jamia Millia Islamia
Format: Article
Published: 2018
Subjects:
Chemical Engineering
Chemistry
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/43406
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/43406

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