Genetic diversity of the Plasmodium vivax multidrug resistance 1 gene in Thai parasite populations

• Main Authors: Veerayuth Kittichai, Wang Nguitragool, Huguette Gaelle Ngassa Mbenda, Jetsumon Sattabongkot, Liwang Cui
• Other Authors: King Mongkut's Institute of Technology Ladkrabang
• Format: Article
• Published: 2019
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/44668
• Institution: Mahidol University

© 2018 Elsevier B.V. Plasmodium vivax resistance to chloroquine (CQ) was first reported over 60 years ago. Here we analyzed sequence variations in the multidrug resistance 1 gene (Pvmdr1), a putative molecular marker for P. vivax CQ resistance, in field isolates collected from three sites in Thailan...