Recombination hotspots in an extended human pseudoautosomal domain predicted from double-strand break maps and characterized by sperm-based crossover analysis

• Main Authors: Nitikorn Poriswanish, Rita Neumann, Jon H. Wetton, John Wagstaff, Maarten H.D. Larmuseau, Mark A. Jobling, Celia A. May
• Other Authors: University of Leicester
• Format: Article
• Published: 2019
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/44672
• Institution: Mahidol University

© 2018 Poriswanish et al. http://creativecommons.org/licenses/by/4.0/. The human X and Y chromosomes are heteromorphic but share a region of homology at the tips of their short arms, pseudoautosomal region 1 (PAR1), that supports obligate crossover in male meiosis. Although the boundary between pseu...