CX-4945 induces methuosis in cholangiocarcinoma cell lines by a CK2-independent mechanism

• Main Authors: Jomnarong Lertsuwan, Kornkamon Lertsuwan, Anyaporn Sawasdichai, Nathapol Tasnawijitwong, Ka Ying Lee, Philip Kitchen, Simon Afford, Kevin Gaston, Padma Sheela Jayaraman, Jutamaad Satayavivad
• Other Authors: Chulabhorn Research Institute
• Format: Article
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/45064
• Institution: Mahidol University

© 2018 by the authors. Licensee MDPI, Basel, Switzerland. Cholangiocarcinoma is a disease with a poor prognosis and increasing incidence and hence there is a pressing unmet clinical need for new adjuvant treatments. Protein kinase CK2 (previously casein kinase II) is a ubiquitously expressed protein...