DABCO-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides

© 2018 The Royal Society of Chemistry. A highly efficient protocol for a direct thiolation of N-substituted pyrazolones with diaryl disulfides is described. Using a combination of DABCO and silver(i) acetate, the C-S bond formation proceeds smoothly at room temperature under mild and easy to handle...

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Main Authors:	Akkharaphong Thupyai, Chaleena Pimpasri, Sirilata Yotphan
Other Authors:	Mahidol University
Format:	Article
Published:	2019
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry
Online Access:	https://repository.li.mahidol.ac.th/handle/123456789/45275
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Institution:	Mahidol University

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spelling	th-mahidol.452752019-08-23T17:52:06Z DABCO-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides Akkharaphong Thupyai Chaleena Pimpasri Sirilata Yotphan Mahidol University Biochemistry, Genetics and Molecular Biology Chemistry © 2018 The Royal Society of Chemistry. A highly efficient protocol for a direct thiolation of N-substituted pyrazolones with diaryl disulfides is described. Using a combination of DABCO and silver(i) acetate, the C-S bond formation proceeds smoothly at room temperature under mild and easy to handle conditions. This synthetic strategy offers a convenient and direct modification of antipyrine and other pyrazolone substrates, giving a series of aryl sulfide-substituted pyrazolone products in moderate to excellent yields. 2019-08-23T10:38:40Z 2019-08-23T10:38:40Z 2018-01-01 Article Organic and Biomolecular Chemistry. Vol.16, No.3 (2018), 424-432 10.1039/c7ob02860a 14770520 2-s2.0-85040903440 https://repository.li.mahidol.ac.th/handle/123456789/45275 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85040903440&origin=inward
institution	Mahidol University
building	Mahidol University Library
continent	Asia
country	Thailand Thailand
content_provider	Mahidol University Library
collection	Mahidol University Institutional Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Akkharaphong Thupyai Chaleena Pimpasri Sirilata Yotphan DABCO-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides
description	© 2018 The Royal Society of Chemistry. A highly efficient protocol for a direct thiolation of N-substituted pyrazolones with diaryl disulfides is described. Using a combination of DABCO and silver(i) acetate, the C-S bond formation proceeds smoothly at room temperature under mild and easy to handle conditions. This synthetic strategy offers a convenient and direct modification of antipyrine and other pyrazolone substrates, giving a series of aryl sulfide-substituted pyrazolone products in moderate to excellent yields.
author2	Mahidol University
author_facet	Mahidol University Akkharaphong Thupyai Chaleena Pimpasri Sirilata Yotphan
format	Article
author	Akkharaphong Thupyai Chaleena Pimpasri Sirilata Yotphan
author_sort	Akkharaphong Thupyai
title	DABCO-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides
title_short	DABCO-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides
title_full	DABCO-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides
title_fullStr	DABCO-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides
title_full_unstemmed	DABCO-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides
title_sort	dabco-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides
publishDate	2019
url	https://repository.li.mahidol.ac.th/handle/123456789/45275
_version_	1763494509653524480

DABCO-catalyzed silver-promoted direct thiolation of pyrazolones with diaryl disulfides

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