Nitric oxide promotes cancer cell dedifferentiation by disrupting an Oct4:caveolin-1 complex: A new regulatory mechanism for cancer stem cell formation

• Main Authors: Arnatchai Maiuthed, Narumol Bhummaphan, Sudjit Luanpitpong, Apiwat Mutirangura, Chatchawit Aporntewan, Arthitaya Meeprasert, Thanyada Rungrotmongkol, Yon Rojanasakul, Pithi Chanvorachote
• Other Authors: Chulalongkorn University
• Format: Article
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/45334
• Institution: Mahidol University

© 2018 by The American Society for Biochemistry and Molecular Biology, Inc. Cancer stem cells (CSCs) are unique populations of cells that can self-renew and generate different cancer cell lineages. Although CSCs are believed to be a promising target for novel therapies, the specific mechanisms by w...