Notch signaling in macrophages in the context of cancer immunity

• Main Authors: Tanapat Palaga, Wipawee Wongchana, Patipark Kueanjinda
• Other Authors: Chulalongkorn University
• Format: Review
• Published: 2019
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/46023
• Institution: Mahidol University

© 2018 Palaga, Wongchana and Kueanjinda. Macrophages play both tumor-suppressing and tumor-promoting roles depending on the microenvironment. Tumor-associated macrophages (TAMs) are often associated with poor prognosis in most, but not all cancer. Understanding how macrophages become TAMs and how TA...