Fitness costs and the rapid spread of kelch13-C580Y substitutions conferring artemisinin resistance
Copyright © 2018 Nair et al. Fitness costs are key determinants of whether drug resistance alleles establish and how fast they spread within populations. More than 125 different kelch13 alleles, each containing a different amino acid substitution, have arisen in Southeast Asian malaria parasite (Pla...
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Main Authors: | , , , , , , |
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Format: | Article |
Published: |
2019
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/46403 |
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Institution: | Mahidol University |