International multicenter observational study on assessment of ventilatory management during general anaesthesia for robotic surgery and its effects on postoperative pulmonary complication (AVATaR): Study protocol and statistical analysis plan

• Main Authors: Veronica Neves Fialho Queiroz, Luiz Guilherme Villares Da Costa, Rogerio Póvoa Barbosa, Flávio Takaoka, Luc De Baerdemaeker, Daniel Souza Cesar, Ulisses Cardoso D'Orto, José Roberto Galdi, Vijaya Gottumukkala, Juan P. Cata, Sabrine N.T. Hemmes, Markus W. Hollman, Alain Kalmar, Lucas A.B. De Moura, Renato M. Mariano, Idit Matot, Guido Mazzinari, Gary H. Mills, Irimar De Paula Posso, Alexandre Teruya, Marcos Francisco Vidal Melo, Juraj Sprung, Toby N. Weingarten, Tanja A. Treschan, Seppe Koopman, Leonid Eidelman, Lee Lynn Chen, Jae Woo Lee, Jose J. Ariño Irujo, Beatriz Tena, Harald Groeben, Paolo Pelosi, Marcelo Gama De Abreu, Marcus J. Schultz, Ary Serpa Neto, Juan Catala, Mauro Bravo, Renato Carneir De Freitas, Chaves Felipe, Rothman Bruno, Schuind Arantes, Dina Mie Hatanaka, Joan Beltran, Concepción Monsalve, Sijgje Mari Droger, Atousa Deljou, Moldovan Sabov, Yosef Sale Rabbu, Marina Del Barrio De Bonis, Renate Babian, Robert Rabenalt, Wiebke Köhne, Ariel Ronen, Aalok V. Agarwala, Manuel Granell
• Other Authors: Ospedale Policlinico San Martino
• Format: Article
• Published: 2019
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/46497
• Institution: Mahidol University

© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Robotic-assisted surgery (RAS) has emerged as an alternative minimally invasive surgical option. Despite its growing applicability, the frequent need for pneumoperitoneum and Trendelenburg position could significantly affect respiratory mechanics during RAS. AVATaR is an international multicenter observational study aiming to assess the incidence of postoperative pulmonary complications (PPC), to characterise current practices of mechanical ventilation (MV) and to evaluate a possible association between ventilatory parameters and PPC in patients undergoing RAS. Methods and analysis AVATaR is an observational study of surgical patients undergoing MV for general anaesthesia for RAS. The primary outcome is the incidence of PPC during the first five postoperative days. Secondary outcomes include practice of MV, effect of surgical positioning on MV, effect of MV on clinical outcome and intraoperative complications. Ethics and dissemination This study was approved by the Institutional Review Board of the Hospital Israelita Albert Einstein. The study results will be published in peer-reviewed journals and disseminated at international conferences. Trial registration number NCT02989415; Pre-results.