Long-term outcomes of cement in cement technique for revision endoprosthesis surgery

© 2017 Wiley Periodicals, Inc. Background and Objective: Cemented endoprosthetic reconstruction after resection of primary bone sarcomas has been a standard-of-care option for decades. With increased patient survival, the incidence of failed endoprostheses requiring revision surgery has increased. R...

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Main Authors: Nicholas M. Bernthal, Vishal Hegde, Stephen D. Zoller, Howard Y. Park, Jason H. Ghodasra, Daniel Johansen, Frederick Eilber, Fritz C. Eilber, Chandhanarat Chandhanayingyong, Jeffrey J. Eckardt
Other Authors: University of California, Los Angeles
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Published: 2019
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/46909
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spelling th-mahidol.469092019-08-28T13:22:00Z Long-term outcomes of cement in cement technique for revision endoprosthesis surgery Nicholas M. Bernthal Vishal Hegde Stephen D. Zoller Howard Y. Park Jason H. Ghodasra Daniel Johansen Frederick Eilber Fritz C. Eilber Chandhanarat Chandhanayingyong Jeffrey J. Eckardt University of California, Los Angeles Faculty of Medicine, Siriraj Hospital, Mahidol University David Geffen School of Medicine at UCLA Medicine © 2017 Wiley Periodicals, Inc. Background and Objective: Cemented endoprosthetic reconstruction after resection of primary bone sarcomas has been a standard-of-care option for decades. With increased patient survival, the incidence of failed endoprostheses requiring revision surgery has increased. Revision of cemented endoprotheses by cementing into the existing cement mantle (CiC) is technically demanding. Methods: This is a retrospective review of our endoprosthesis database of 512 consecutive cemented endoprosthetic reconstructions performed for oncologic diagnoses between 1980 and 2014. A total of 54 implants (mean patient age 32 years, range 13-81) were revised with a CiC technique. Outcomes evaluated were prosthesis survival, revision surgery categorized according to the Henderson Failure Mode Classification, complications, and functional scores. Results: Fifteen-year Kaplan-Meier survival rate was 34% for initial revision and 39% for subsequent revision implants. Mean revised Musculoskeletal Tumor Society (MSTS) Score was 27 at latest follow-up. Infection rate was 2%, 9%, and 13% for primary endoprostheses, initial revisions, and subsequent revisions, respectively. Limb salvage rate was 87%. Conclusions: At long-term follow up, endoprostheses revised with the CiC technique showed consistent 15-year survival from initial (34%) to subsequent (39%) revision. Despite a relatively high failure rate, these results are encouraging and demonstrate that this is a conservative, repeatable technique. 2019-08-28T06:22:00Z 2019-08-28T06:22:00Z 2018-03-01 Article Journal of Surgical Oncology. Vol.117, No.3 (2018), 443-450 10.1002/jso.24862 10969098 00224790 2-s2.0-85032333951 https://repository.li.mahidol.ac.th/handle/123456789/46909 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85032333951&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Nicholas M. Bernthal
Vishal Hegde
Stephen D. Zoller
Howard Y. Park
Jason H. Ghodasra
Daniel Johansen
Frederick Eilber
Fritz C. Eilber
Chandhanarat Chandhanayingyong
Jeffrey J. Eckardt
Long-term outcomes of cement in cement technique for revision endoprosthesis surgery
description © 2017 Wiley Periodicals, Inc. Background and Objective: Cemented endoprosthetic reconstruction after resection of primary bone sarcomas has been a standard-of-care option for decades. With increased patient survival, the incidence of failed endoprostheses requiring revision surgery has increased. Revision of cemented endoprotheses by cementing into the existing cement mantle (CiC) is technically demanding. Methods: This is a retrospective review of our endoprosthesis database of 512 consecutive cemented endoprosthetic reconstructions performed for oncologic diagnoses between 1980 and 2014. A total of 54 implants (mean patient age 32 years, range 13-81) were revised with a CiC technique. Outcomes evaluated were prosthesis survival, revision surgery categorized according to the Henderson Failure Mode Classification, complications, and functional scores. Results: Fifteen-year Kaplan-Meier survival rate was 34% for initial revision and 39% for subsequent revision implants. Mean revised Musculoskeletal Tumor Society (MSTS) Score was 27 at latest follow-up. Infection rate was 2%, 9%, and 13% for primary endoprostheses, initial revisions, and subsequent revisions, respectively. Limb salvage rate was 87%. Conclusions: At long-term follow up, endoprostheses revised with the CiC technique showed consistent 15-year survival from initial (34%) to subsequent (39%) revision. Despite a relatively high failure rate, these results are encouraging and demonstrate that this is a conservative, repeatable technique.
author2 University of California, Los Angeles
author_facet University of California, Los Angeles
Nicholas M. Bernthal
Vishal Hegde
Stephen D. Zoller
Howard Y. Park
Jason H. Ghodasra
Daniel Johansen
Frederick Eilber
Fritz C. Eilber
Chandhanarat Chandhanayingyong
Jeffrey J. Eckardt
format Article
author Nicholas M. Bernthal
Vishal Hegde
Stephen D. Zoller
Howard Y. Park
Jason H. Ghodasra
Daniel Johansen
Frederick Eilber
Fritz C. Eilber
Chandhanarat Chandhanayingyong
Jeffrey J. Eckardt
author_sort Nicholas M. Bernthal
title Long-term outcomes of cement in cement technique for revision endoprosthesis surgery
title_short Long-term outcomes of cement in cement technique for revision endoprosthesis surgery
title_full Long-term outcomes of cement in cement technique for revision endoprosthesis surgery
title_fullStr Long-term outcomes of cement in cement technique for revision endoprosthesis surgery
title_full_unstemmed Long-term outcomes of cement in cement technique for revision endoprosthesis surgery
title_sort long-term outcomes of cement in cement technique for revision endoprosthesis surgery
publishDate 2019
url https://repository.li.mahidol.ac.th/handle/123456789/46909
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