SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation
© 2017 American Academy of Allergy, Asthma & Immunology Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening, immunologically mediated, and usually drug-induced disease with a high burden to individuals, their families, and society with an annual incidence of 1 t...
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Medicine Katie D. White Riichiro Abe Michael Ardern-Jones Thomas Beachkofsky Charles Bouchard Bruce Carleton James Chodosh Ricardo Cibotti Robert Davis Joshua C. Denny Roni P. Dodiuk-Gad Elizabeth N. Ergen Jennifer L. Goldman James H. Holmes Shuen Iu Hung Mario E. Lacouture Rannakoe J. Lehloenya Simon Mallal Teri A. Manolio Robert G. Micheletti Caroline M. Mitchell Maja Mockenhaupt David A. Ostrov Rebecca Pavlos Munir Pirmohamed Elena Pope Alec Redwood Misha Rosenbach Michael D. Rosenblum Jean Claude Roujeau Arturo P. Saavedra Hajirah N. Saeed Jeffery P. Struewing Hirohiko Sueki Chonlaphat Sukasem Cynthia Sung Jason A. Trubiano Jessica Weintraub Lisa M. Wheatley Kristina B. Williams Brandon Worley Wen Hung Chung Neil H. Shear Elizabeth J. Phillips SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation |
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© 2017 American Academy of Allergy, Asthma & Immunology Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening, immunologically mediated, and usually drug-induced disease with a high burden to individuals, their families, and society with an annual incidence of 1 to 5 per 1,000,000. To effect significant reduction in short- and long-term morbidity and mortality, and advance clinical care and research, coordination of multiple medical, surgical, behavioral, and basic scientific disciplines is required. On March 2, 2017, an investigator-driven meeting was held immediately before the American Academy of Dermatology Annual meeting for the central purpose of assembling, for the first time in the United States, clinicians and scientists from multiple disciplines involved in SJS/TEN clinical care and basic science research. As a product of this meeting, this article summarizes the current state of knowledge and expert opinion related to SJS/TEN covering a broad spectrum of topics including epidemiology and pharmacogenomic networks; clinical management and complications; special populations such as pediatrics, the elderly, and pregnant women; regulatory issues and the electronic health record; new agents that cause SJS/TEN; pharmacogenomics and immunopathogenesis; and the patient perspective. Goals include the maintenance of a durable and productive multidisciplinary network that will significantly further scientific progress and translation into prevention, early diagnosis, and management of SJS/TEN. |
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Duke-NUS Medical School Singapore |
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Duke-NUS Medical School Singapore Katie D. White Riichiro Abe Michael Ardern-Jones Thomas Beachkofsky Charles Bouchard Bruce Carleton James Chodosh Ricardo Cibotti Robert Davis Joshua C. Denny Roni P. Dodiuk-Gad Elizabeth N. Ergen Jennifer L. Goldman James H. Holmes Shuen Iu Hung Mario E. Lacouture Rannakoe J. Lehloenya Simon Mallal Teri A. Manolio Robert G. Micheletti Caroline M. Mitchell Maja Mockenhaupt David A. Ostrov Rebecca Pavlos Munir Pirmohamed Elena Pope Alec Redwood Misha Rosenbach Michael D. Rosenblum Jean Claude Roujeau Arturo P. Saavedra Hajirah N. Saeed Jeffery P. Struewing Hirohiko Sueki Chonlaphat Sukasem Cynthia Sung Jason A. Trubiano Jessica Weintraub Lisa M. Wheatley Kristina B. Williams Brandon Worley Wen Hung Chung Neil H. Shear Elizabeth J. Phillips |
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Review |
author |
Katie D. White Riichiro Abe Michael Ardern-Jones Thomas Beachkofsky Charles Bouchard Bruce Carleton James Chodosh Ricardo Cibotti Robert Davis Joshua C. Denny Roni P. Dodiuk-Gad Elizabeth N. Ergen Jennifer L. Goldman James H. Holmes Shuen Iu Hung Mario E. Lacouture Rannakoe J. Lehloenya Simon Mallal Teri A. Manolio Robert G. Micheletti Caroline M. Mitchell Maja Mockenhaupt David A. Ostrov Rebecca Pavlos Munir Pirmohamed Elena Pope Alec Redwood Misha Rosenbach Michael D. Rosenblum Jean Claude Roujeau Arturo P. Saavedra Hajirah N. Saeed Jeffery P. Struewing Hirohiko Sueki Chonlaphat Sukasem Cynthia Sung Jason A. Trubiano Jessica Weintraub Lisa M. Wheatley Kristina B. Williams Brandon Worley Wen Hung Chung Neil H. Shear Elizabeth J. Phillips |
author_sort |
Katie D. White |
title |
SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation |
title_short |
SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation |
title_full |
SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation |
title_fullStr |
SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation |
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SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation |
title_sort |
sjs/ten 2017: building multidisciplinary networks to drive science and translation |
publishDate |
2019 |
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https://repository.li.mahidol.ac.th/handle/123456789/47258 |
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th-mahidol.472582019-08-28T13:41:20Z SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation Katie D. White Riichiro Abe Michael Ardern-Jones Thomas Beachkofsky Charles Bouchard Bruce Carleton James Chodosh Ricardo Cibotti Robert Davis Joshua C. Denny Roni P. Dodiuk-Gad Elizabeth N. Ergen Jennifer L. Goldman James H. Holmes Shuen Iu Hung Mario E. Lacouture Rannakoe J. Lehloenya Simon Mallal Teri A. Manolio Robert G. Micheletti Caroline M. Mitchell Maja Mockenhaupt David A. Ostrov Rebecca Pavlos Munir Pirmohamed Elena Pope Alec Redwood Misha Rosenbach Michael D. Rosenblum Jean Claude Roujeau Arturo P. Saavedra Hajirah N. Saeed Jeffery P. Struewing Hirohiko Sueki Chonlaphat Sukasem Cynthia Sung Jason A. Trubiano Jessica Weintraub Lisa M. Wheatley Kristina B. Williams Brandon Worley Wen Hung Chung Neil H. Shear Elizabeth J. Phillips Duke-NUS Medical School Singapore National Yang-Ming University Taiwan Chang Gung Memorial Hospital Wake Forest University School of Medicine Health Sciences Authority, Government of Singapore Vanderbilt University Medical Center Hospital for Sick Children University of Toronto Massachusetts General Hospital University of Ottawa, Canada Showa University School of Medicine Niigata University School of Medicine The University of Alabama at Birmingham University of Melbourne Wake Forest University Baptist Medical Center Universität Freiburg im Breisgau University of Southampton Universite Paris 12 Val de Marne University of California, San Francisco Technion - Israel Institute of Technology University of Liverpool Murdoch University Children's Mercy Hospitals and Clinics National Institute of Allergy and Infectious Diseases Loyola University Medical Center University of Toronto Faculty of Medicine, Ramathibodi Hospital, Mahidol University University of Florida National Human Genome Research Institute The University of British Columbia Food and Drug Administration Memorial Sloan-Kettering Cancer Center BC Children's Hospital Uniformed Services University of the Health Sciences University of Pennsylvania National Institute of Arthritis and Musculoskeletal and Skin Diseases Austin Health Groote Schuur Hospital Harvard Medical School University of Tennessee Health Science Center Lackland Air Force Base Medicine © 2017 American Academy of Allergy, Asthma & Immunology Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening, immunologically mediated, and usually drug-induced disease with a high burden to individuals, their families, and society with an annual incidence of 1 to 5 per 1,000,000. To effect significant reduction in short- and long-term morbidity and mortality, and advance clinical care and research, coordination of multiple medical, surgical, behavioral, and basic scientific disciplines is required. On March 2, 2017, an investigator-driven meeting was held immediately before the American Academy of Dermatology Annual meeting for the central purpose of assembling, for the first time in the United States, clinicians and scientists from multiple disciplines involved in SJS/TEN clinical care and basic science research. As a product of this meeting, this article summarizes the current state of knowledge and expert opinion related to SJS/TEN covering a broad spectrum of topics including epidemiology and pharmacogenomic networks; clinical management and complications; special populations such as pediatrics, the elderly, and pregnant women; regulatory issues and the electronic health record; new agents that cause SJS/TEN; pharmacogenomics and immunopathogenesis; and the patient perspective. Goals include the maintenance of a durable and productive multidisciplinary network that will significantly further scientific progress and translation into prevention, early diagnosis, and management of SJS/TEN. 2019-08-28T06:41:20Z 2019-08-28T06:41:20Z 2018-01-01 Review Journal of Allergy and Clinical Immunology: In Practice. Vol.6, No.1 (2018), 38-69 10.1016/j.jaip.2017.11.023 22132198 2-s2.0-85041346868 https://repository.li.mahidol.ac.th/handle/123456789/47258 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85041346868&origin=inward |