Persistence of Long-lived Memory B Cells specific to Duffy Binding Protein in individuals exposed to Plasmodium vivax

• Main Authors: Siriruk Changrob, Amy M. McHenry, Myat Htut Nyunt, Jetsumon Sattabongkot, Eun Taek Han, John H. Adams, Patchanee Chootong
• Other Authors: Mahidol University
• Format: Article
• Published: 2019
• Subjects: Multidisciplinary
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/47484

© 2018 The Author(s). The major challenge in designing a protective Duffy binding protein region II (DBPII)-based vaccine against blood-stage vivax malaria is the high number of polymorphisms in critical residues targeted by binding-inhibitory antibodies. Here, longevity of antibody and memory B cel...