Parathyroid hormone increases CFTR expression and function in Caco-2 intestinal epithelial cells

• Main Authors: Walailak Jantarajit, Kannikar Wongdee, Kornkamon Lertsuwan, Jarinthorn Teerapornpuntakit, Ratchaneevan Aeimlapa, Jirawan Thongbunchoo, Bartholomew S.J. Harvey, David N. Sheppard, Narattaphol Charoenphandhu
• Other Authors: Naresuan University
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/49555
• Institution: Mahidol University

© 2020 Elsevier Inc. Parathyroid hormone (PTH) enhances cystic fibrosis transmembrane conductance regulator (CFTR)-mediated anion secretion by the human intestinal epithelial cell line Caco-2. With the patch-clamp and Ussing chamber techniques, we investigated how PTH stimulates CFTR activity in Cac...