Metformin restores the mitochondrial membrane potentials in association with a reduction in TIMM23 and NDUFS3 in MPP⁺-induced neurotoxicity in SH-SY5Y cells

• Main Authors: Pitak Chanthammachat, Permphan Dharmasaroja
• Other Authors: Mahidol University
• Format: Article
• Published: 2020
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/49844

© 2019, Leibniz Research Centre for Working Environment and Human Factors. All rights reserved. SH-SY5Y cells exposed to l-methyl-4-phenylpyridinium (MPP+) develop mitochondrial dysfunction and other cellular responses similar to those that occur in the dopaminergic neurons of patients with Parkinso...