Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria
© 2019 The Authors Methylmalonic acidemia (MMA) is a propionate pathway disorder caused by dysfunction of the mitochondrial enzyme methylmalonyl-CoA mutase (MMUT). MMUT catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA, an anaplerotic reaction which feeds into the tricarboxylic acid (TCA...
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Main Authors: | , , , , , , |
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Format: | Article |
Published: |
2020
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/50017 |
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Institution: | Mahidol University |