CRISPR-Cas3 induces broad and unidirectional genome editing in human cells
© 2019, The Author(s). Although single-component Class 2 CRISPR systems, such as type II Cas9 or type V Cas12a (Cpf1), are widely used for genome editing in eukaryotic cells, the application of multi-component Class 1 CRISPR has been less developed. Here we demonstrate that type I-E CRISPR mediates...
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Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Published: |
2020
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/50021 |
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Institution: | Mahidol University |