Inhibition of human UDP-glucuronosyltransferase (UGT) enzymes by kinase inhibitors: Effects of dabrafenib, ibrutinib, nintedanib, trametinib and BIBF 1202
© 2019 We have demonstrated previously that the kinase inhibitors (KIs) lapatinib, pazopanib, regorafenib and sorafenib are potent inhibitors of UGT1A1 and UGTs 1A7-1A10. The present study characterised the effects of four additional drugs in this class, dabrafenib, ibrutinib, nintedanib and trameti...
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Main Authors: | , , , , |
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Format: | Article |
Published: |
2020
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/50041 |
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Institution: | Mahidol University |