Unified synthesis and cytotoxic activity of 8-O -methylfusarubin and its analogues

• Main Authors: Pongsit Vijitphan, Vatcharin Rukachaisirikul, Chatchai Muanprasat, Panata Iawsipo, Jiraporn Panprasert, Kwanruthai Tadpetch
• Other Authors: Mahidol University
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/50359

© 2019 The Royal Society of Chemistry. A simple and unified synthesis of four related pyranonaphthoquinone natural products, e.g. 8-O-methylfusarubin, 8-O-methylanhydrofusarubin, fusarubin and anhydrofusarubin, is reported. The key synthetic features include the precedented Diels-Alder cycloaddition...