Optimization and Standardization of Thermal Treatment as a Plasma Prefractionation Method for Proteomic Analysis

• Main Authors: Wararat Chiangjong, Channarong Changtong, Jirawan Panachan, Churat Weeraphan, Chantragan Srisomsap, Suradej Hongeng, Jisnuson Svasti, Somchai Chutipongtanate
• Other Authors: Chulabhorn Research Institute
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/50392
• Institution: Mahidol University

© 2019 Wararat Chiangjong et al. Prefractionation is a prerequisite step for deep plasma proteomics. Highly abundant proteins, particularly human serum albumin (HSA) and immunoglobulin G (IgG), typically interfere with investigation of proteins with lower abundance. A relatively simple preparation m...