Biomarkers in stress related diseases/disorders: Diagnostic, prognostic, and therapeutic values

© 2019 Dhama, Latheef, Dadar, Samad, Munjal, Khandia, Karthik, Tiwari, Yatoo, Bhatt, Chakraborty, Singh, Iqbal, Chaicumpa and Joshi. Various internal and external factors negatively affect the homeostatic equilibrium of organisms at the molecular to the whole-body level, inducing the so-called state...

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Main Authors: Kuldeep Dhama, Shyma K. Latheef, Maryam Dadar, Hari Abdul Samad, Ashok Munjal, Rekha Khandia, Kumaragurubaran Karthik, Ruchi Tiwari, Mohd Iqbal Yatoo, Prakash Bhatt, Sandip Chakraborty, Karam Pal Singh, Hafiz M.N. Iqbal, Wanpen Chaicumpa, Sunil Kumar Joshi
Other Authors: Razi Vaccine & Serum Research Institute, Iran
Format: Review
Published: 2020
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/50409
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spelling th-mahidol.504092020-01-27T15:00:01Z Biomarkers in stress related diseases/disorders: Diagnostic, prognostic, and therapeutic values Kuldeep Dhama Shyma K. Latheef Maryam Dadar Hari Abdul Samad Ashok Munjal Rekha Khandia Kumaragurubaran Karthik Ruchi Tiwari Mohd Iqbal Yatoo Prakash Bhatt Sandip Chakraborty Karam Pal Singh Hafiz M.N. Iqbal Wanpen Chaicumpa Sunil Kumar Joshi Razi Vaccine & Serum Research Institute, Iran Tamilnadu Veterinary Animal Sciences University Barkatullah University University of Miami Leonard M. Miller School of Medicine Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir College of Veterinary Science India Govind Ballabh Pant University of Agriculture and Technology Faculty of Medicine, Siriraj Hospital, Mahidol University Tecnologico de Monterrey Indian Veterinary Research Institute College of Veterinary Sciences and Animal Husbandry Biochemistry, Genetics and Molecular Biology © 2019 Dhama, Latheef, Dadar, Samad, Munjal, Khandia, Karthik, Tiwari, Yatoo, Bhatt, Chakraborty, Singh, Iqbal, Chaicumpa and Joshi. Various internal and external factors negatively affect the homeostatic equilibrium of organisms at the molecular to the whole-body level, inducing the so-called state of stress. Stress affects an organism’s welfare status and induces energy-consuming mechanisms to combat the subsequent ill effects; thus, the individual may be immunocompromised, making them vulnerable to pathogens. The information presented here has been extensively reviewed, compiled, and analyzed from authenticated published resources available on Medline, PubMed, PubMed Central, Science Direct, and other scientific databases. Stress levels can be monitored by the quantitative and qualitative measurement of biomarkers. Potential markers of stress include thermal stress markers, such as heat shock proteins (HSPs), innate immune markers, such as Acute Phase Proteins (APPs), oxidative stress markers, and chemical secretions in the saliva and urine. In addition, stress biomarkers also play critical roles in the prognosis of stress-related diseases and disorders, and therapy guidance. Moreover, different components have been identified as potent mediators of cardiovascular, central nervous system, hepatic, and nephrological disorders, which can also be employed to evaluate these conditions precisely, but with stringent validation and specificity. Considerable scientific advances have been made in the detection, quantitation, and application of these biomarkers. The present review describes the current progress of identifying biomarkers, their prognostic, and therapeutic values. 2020-01-27T08:00:01Z 2020-01-27T08:00:01Z 2019-01-01 Review Frontiers in Molecular Biosciences. Vol.6, (2019) 10.3389/fmolb.2019.00091 2296889X 2-s2.0-85074725671 https://repository.li.mahidol.ac.th/handle/123456789/50409 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85074725671&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Biochemistry, Genetics and Molecular Biology
spellingShingle Biochemistry, Genetics and Molecular Biology
Kuldeep Dhama
Shyma K. Latheef
Maryam Dadar
Hari Abdul Samad
Ashok Munjal
Rekha Khandia
Kumaragurubaran Karthik
Ruchi Tiwari
Mohd Iqbal Yatoo
Prakash Bhatt
Sandip Chakraborty
Karam Pal Singh
Hafiz M.N. Iqbal
Wanpen Chaicumpa
Sunil Kumar Joshi
Biomarkers in stress related diseases/disorders: Diagnostic, prognostic, and therapeutic values
description © 2019 Dhama, Latheef, Dadar, Samad, Munjal, Khandia, Karthik, Tiwari, Yatoo, Bhatt, Chakraborty, Singh, Iqbal, Chaicumpa and Joshi. Various internal and external factors negatively affect the homeostatic equilibrium of organisms at the molecular to the whole-body level, inducing the so-called state of stress. Stress affects an organism’s welfare status and induces energy-consuming mechanisms to combat the subsequent ill effects; thus, the individual may be immunocompromised, making them vulnerable to pathogens. The information presented here has been extensively reviewed, compiled, and analyzed from authenticated published resources available on Medline, PubMed, PubMed Central, Science Direct, and other scientific databases. Stress levels can be monitored by the quantitative and qualitative measurement of biomarkers. Potential markers of stress include thermal stress markers, such as heat shock proteins (HSPs), innate immune markers, such as Acute Phase Proteins (APPs), oxidative stress markers, and chemical secretions in the saliva and urine. In addition, stress biomarkers also play critical roles in the prognosis of stress-related diseases and disorders, and therapy guidance. Moreover, different components have been identified as potent mediators of cardiovascular, central nervous system, hepatic, and nephrological disorders, which can also be employed to evaluate these conditions precisely, but with stringent validation and specificity. Considerable scientific advances have been made in the detection, quantitation, and application of these biomarkers. The present review describes the current progress of identifying biomarkers, their prognostic, and therapeutic values.
author2 Razi Vaccine & Serum Research Institute, Iran
author_facet Razi Vaccine & Serum Research Institute, Iran
Kuldeep Dhama
Shyma K. Latheef
Maryam Dadar
Hari Abdul Samad
Ashok Munjal
Rekha Khandia
Kumaragurubaran Karthik
Ruchi Tiwari
Mohd Iqbal Yatoo
Prakash Bhatt
Sandip Chakraborty
Karam Pal Singh
Hafiz M.N. Iqbal
Wanpen Chaicumpa
Sunil Kumar Joshi
format Review
author Kuldeep Dhama
Shyma K. Latheef
Maryam Dadar
Hari Abdul Samad
Ashok Munjal
Rekha Khandia
Kumaragurubaran Karthik
Ruchi Tiwari
Mohd Iqbal Yatoo
Prakash Bhatt
Sandip Chakraborty
Karam Pal Singh
Hafiz M.N. Iqbal
Wanpen Chaicumpa
Sunil Kumar Joshi
author_sort Kuldeep Dhama
title Biomarkers in stress related diseases/disorders: Diagnostic, prognostic, and therapeutic values
title_short Biomarkers in stress related diseases/disorders: Diagnostic, prognostic, and therapeutic values
title_full Biomarkers in stress related diseases/disorders: Diagnostic, prognostic, and therapeutic values
title_fullStr Biomarkers in stress related diseases/disorders: Diagnostic, prognostic, and therapeutic values
title_full_unstemmed Biomarkers in stress related diseases/disorders: Diagnostic, prognostic, and therapeutic values
title_sort biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values
publishDate 2020
url https://repository.li.mahidol.ac.th/handle/123456789/50409
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