Metabolic Profiling and Compound-Class Identification Reveal Alterations in Serum Triglyceride Levels in Mice Immunized with Human Vaccine Adjuvant Alum

• Main Authors: Sakda Khoomrung, Intawat Nookaew, Partho Sen, Thorunn A. Olafsdottir, Josefine Persson, Thomas Moritz, Peter Andersen, Ali M. Harandi, Jens Nielsen
• Other Authors: Göteborgs universitet, Institutionen för biomedicin
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/50410
• Institution: Mahidol University

Copyright © 2019 American Chemical Society. Alum has been widely used as an adjuvant for human vaccines; however, the impact of Alum on host metabolism remains largely unknown. Herein, we applied mass spectrometry (MS) (liquid chromatography-MS)-based metabolic and lipid profiling to monitor the eff...