Hybridization Cascade Plus Strand-Displacement Isothermal Amplification of RNA Target with Secondary Structure Motifs and Its Application for Detecting Dengue and Zika Viruses

• Main Authors: W. Saisuk, C. Srisawat, S. Yoksan, T. Dharakul
• Other Authors: Mahidol University
• Format: Article
• Published: 2020
• Subjects: Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/50576

© 2019 American Chemical Society. Biological RNA generally comprises secondary structure motifs which cause a problem for target RNA detection by isothermal amplification methods. The complexity of the secondary structures makes RNA targets inaccessible for probe hybridization, resulting in decrease...